A Hybrid Multi-Distance Phase and Broadband Spatially Resolved Spectrometer and Algorithm for Resolving Absolute Concentrations of Chromophores in the Near-Infrared Light Spectrum
نویسندگان
چکیده
For resolving absolute concentration of tissue chromophores in the human adult brain with near-infrared spectroscopy it is necessary to calculate the light scattering and absorption, at multiple wavelengths with some depth resolution. To achieve this we propose an instrumentation configuration that combines multi-distance frequency and broadband spectrometers to quantify chromophores in turbid media by using a hybrid spatially resolved algorithm. Preliminary results in solid phantoms as well as liquid dynamic homogeneous and inhomogeneous phantoms and in-vivo muscle measurements showed encouraging results.
منابع مشابه
Effects of assuming constant optical scattering on haemoglobin concentration measurements using NIRS during a Valsalva Manoeuvre
Resolving for changes in concentration of tissue chromophores in the human adult brain with near-infrared spectroscopy has generally been based on the assumption that optical scattering and pathlength remain constant. We have used a novel hybrid optical spectrometer that combines multi-distance frequency and broadband systems to investigate the changes in scattering and pathlength during a Vals...
متن کاملModeling Time Resolved Light Propagation Inside a Realistic Human Head Model
Background: Near infrared spectroscopy imaging is one of the new techniques used for investigating structural and functionality of different body tissues. This is done by injecting light into the medium and measuring the photon intensity at the surface of the tissue.Method: In this paper the different medical applications, various imaging and simulation techniques of NIRS imaging is described. ...
متن کاملLight Spectrum of Compact Fluorescent Lamps in Iranian Market and Possibility of Hydroxyl Radical Production
Background and purpose: Despite growing use of energy-saving lamps or compact fluorescent lamps (CFLs), there are concerns about ultraviolet radiation in their output. In this study, the output of CFLs available in Iranian market in the range of infrared, visible, and ultraviolet were measured and the possibility of hydroxyl radical production by their radiation was evaluated. Materials and me...
متن کاملDevelopment of a Near Infrared Multi-Wavelength, Multi-Channel, Time-Resolved Spectrometer for Measuring Brain Tissue Haemodynamics and Metabolism
We present a novel time domain functional near infrared spectroscopy system using a supercontinuum laser allowing us to measure the coefficient of absorption and scattering of up to 16 multiplexed wavelengths in the near infrared region. This is a four detector system that generates up to 3 mW of light for each wavelength with a narrow 2-3 nm FWHM bandwidth between 650 and 890 nm; each measurem...
متن کاملChange of Hemoglobin Concentration with nano particles can predict breast cancer using near infrared source?
Introduction: Early detection and treatment of breast cancer may be helping to save the lives of patients. Many new techniques have been urban to detect breast cancer. One of them is the use of nano-particles for accuracy and early diagnosis after photo transfer. In this study, rod gold nano particles was used according their ability to change light source transfer intensity. ...
متن کامل